PIPERIZINYLPIPERIDINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS Russian patent published in 2009 - IPC C07D401/04 A61K31/435 A61P31/12 A61P37/00 

Abstract RU 2369604 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula I, with activity towards chemokine receptor, which can be used for treating immune or viral diseases I, where R1 is heteroaryl; R2 is H, heteroaryl, OR9 or SR9; R3 is F, Cl, Br, I, C1-C4 halogenalkyl or heteroaryl; R4 is C1-C6 alkyl; R5 is C1-C6 alkyl; R9 is H, C1-C6 alkyl, alkoxyalkyl or heteroaryl; r is 1 or 2.

EFFECT: obtaining new biologically active compounds.

33 cl, 30 ex

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RU 2 369 604 C2

Authors

Sjueh Chu-Bjao

Tsao Gan'Fehn

Khuan Tajshehn

Chehn' Likhua

Chzhan Keh

Van An'Laj

Meloni Dehvid

Anand Radzhan

Glenn Dzhozef

Metkaf Brajan

Dates

2009-10-10Published

2005-04-12Filed