FIELD: medicine, pharmaceutics.
SUBSTANCE: inhibitor of influenza A virus reproduction represents water extract of basidial Laetiporus sulphureus, obtained by extraction of crushed fungus biomass with water at ratio 1:1 or 1:2 with further removal of insoluble deposit from extract. Claimed inhibitor demonstrates high inhibiting effect with respect to influenza A virus. Index of virus neutralisation in culture of MDCK cells constitutes 2.5-7 lg. Titres of influenza A virus in homogenates of light infected mice constitute (4.67±0.6)-(6.0±0.57) lgEID50/ml±I95.
EFFECT: high inhibitor activity.
3 cl, 6 tbl, 4 ex
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Authors
Dates
2013-02-20—Published
2011-03-22—Filed