INHIBITOR OF INFLUENZA A VIRUS REPRODUCTION BASED ON EXTRACT OF BASIDIAL FUNGUS Laetiporus sulphureus Russian patent published in 2013 - IPC C12N1/14 A61K36/06 

Abstract RU 2475530 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: inhibitor of influenza A virus reproduction represents water extract of basidial Laetiporus sulphureus, obtained by extraction of crushed fungus biomass with water at ratio 1:1 or 1:2 with further removal of insoluble deposit from extract. Claimed inhibitor demonstrates high inhibiting effect with respect to influenza A virus. Index of virus neutralisation in culture of MDCK cells constitutes 2.5-7 lg. Titres of influenza A virus in homogenates of light infected mice constitute (4.67±0.6)-(6.0±0.57) lgEID50/ml±I95.

EFFECT: high inhibitor activity.

3 cl, 6 tbl, 4 ex

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Authors

Tepljakova Tamara Vladimirovna

Kosogova Tat'Jana Alekseevna

Mazurkova Natal'Ja Alekseevna

Shishkina Larisa Nikolaevna

Kabanov Aleksej Sergeevich

Puchkova Larisa Ivanovna

Sergeev Aleksandr Nikolaevich

Dates

2013-02-20Published

2011-03-22Filed