FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to medicine, namely to formulations containing a human anti-CD20 monoclonal antibodies, a surfactant: polysorbate or poloxamer, trehalose, histidine buffer, to methods for preparing and using it.
EFFECT: group of inventions provides the formulations for enteral introduction of good storage stability at temperature 2-8° and 25°C and good stability at such physical factors, as aggregation, and chemical factors, as fragmentation.
5 cl, 2 ex, 2 tbl
Authors
Dates
2013-02-27—Published
2008-12-11—Filed