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(19)

RU

(11)

2 615 459

(13)

C2

(51)

IPC

C07K16/28(2006-01-01)

C07K16/22(2006-01-01)

A61K39/395(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2013109172, 2011-08-16

(24)

Start date

2011-08-16

(22)

Actual filing date

2011-08-16

(45)

Published

2017-04-04

(72)

Inventor

Gerting FrankKlyajn Kristian

(73)

Holder

Roche Glycart Ag

COMBINED THERAPY BY AFUCOSYLATED ANTIBODY FOR CD20 WITH ANTIBODY FOR VEGF Russian patent published in 2017 - IPC C07K16/28 C07K16/22 A61K39/395 A61P35/00 

Abstract RU 2615459 C2

FIELD: medicine, pharmacy.

SUBSTANCE: invention refers to biotechnology, specifically to combination therapy by afucosylated antibody for CD20 and antibody for VEGF for cancer treatment, which can be used in medicine. A afucosylated humanized B-Ly1 antibody is applied in combination with the antibody for VEGF, with a composition containing tthe said antibodies for treatment of CD20-expressing cancer, and treatment of a patient suffering from CD20-expressing cancer.

EFFECT: invention can effectively inhibit the growth of CD20-expressing tumors.

20 cl, 1 dwg, 2 tbl

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RU 2 615 459 C2

Authors

Gerting Frank

Klyajn Kristian

Dates

2017-04-04—Published

2011-08-16—Filed

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