FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine, namely oncology, and may be used to produce a medicinal product for treating cancer. That is ensured by using a non-fucosylated anti-CD20 antibody with an amount of fucose of 60% or less of a total amount of oligosaccharides (sugars) in Asn297 position in a combination with bendamustine. The above cancer is CD20 expressing cancer, and the above antibody contains an amino acid sequence of VH domain SEQ ID NO: 7 and an amino acid sequence of VL domain SEQ ID NO: 20; what is also presented is a method of treating CD20 expressing cancer.
EFFECT: group of inventions provides treating cancer in patients by synergetic action of the combination of the anti-CD20 antibody and bendamustine.
10 cl, 3 tbl, 1 dwg
