PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND POSSESSING ACTIVITY OF THROMBOPOIETIN RECEPTOR AGONIST, AND INTERMEDIATE COMPOUND THEREFOR Russian patent published in 2013 - IPC C07D277/20 C07D277/46 A61K31/426 A61P7/00 

Abstract RU 2476429 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a pharmaceutical composition containing as an active ingredient an optically active compound presented by formula:

wherein R1 represents a halogen atom or C1-C3alkyloxy; R2 represents C1-C8alkyl; R3 represents C1-C8alkyl; each R4 and R5 independently represents a fluorine atom or a chlorine atom; R6 represents C1-C3alkyl or C1-C3alkyloxy; * specifies that a starred carbon atom is an asymmetric carbon atom, its pharmaceutically acceptable salt or its solvate which possess activity of a thrombopoietin receptor agonist.

EFFECT: preparing the new pharmaceutical composition which possess activity of a thrombopoietin receptor agonist.

12 cl, 5 tbl, 6 dwg, 5 ex

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RU 2 476 429 C2

Authors

Takajama Masami

Kurose Norijuki

Dates

2013-02-27Published

2008-07-29Filed