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2 574 406

(13)

(51)

IPC

C07D401/12(2006-01-01)

C07D207/14(2006-01-01)

C07D401/14(2006-01-01)

C07D409/12(2006-01-01)

C07D413/12(2006-01-01)

C07D413/14(2006-01-01)

C07D417/12(2006-01-01)

C07D417/14(2006-01-01)

A61K31/4025(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2010128620/04, 2006-05-12

(24)

Start date

2006-05-12

(22)

Actual filing date

2006-05-12

(45)

Published

2016-02-10

(72)

Inventor

Kurimura MuneakiTaira SinitiTomojasu TakakhiroIto NobuakiTai KuninoriTakemura NoriakiMatsuzaki TakajukiMendzo JasukhiroMijamura SinSakuraj JokhdziVatanabe AkikhitoSakata JasujoMasumoto TakumiAkazava KokhejSugino KharukhikoAmada NaokiOkhasi SatosiSinokhara TomoitiSasaki KhirofumiMorita TisakoJamasita DzunkoNakadzima Satoko

(73)

Holder

Otsuka Farmas'Jutikal Ko., Ltd.

N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS EFFECTIVE AS MONOAMINE REUPTAKE INHIBITORS Russian patent published in 2016 - IPC C07D401/12 C07D207/14 C07D401/14 C07D409/12 C07D413/12 C07D413/14 C07D417/12 C07D417/14 A61K31/4025 A61P25/00

Abstract RU 2574406 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to versions of a serotonin and/or norepinephrine and/or dopamine reuptake inhibitor applicable for treating disorders caused by reduced serotonin, norepinephrine, or dopamine neurotransmission and containing as an active ingredient a pyrrolidine derivative of general formula (1)

or its pharmaceutically acceptable salt, wherein R¹⁰¹ and R¹⁰² have the values specified in the patent claim.

EFFECT: invention refers to methods of treating various disorders and disturbances involving the declared inhibitors administered.

8 cl, 162 tbl, 1478 ex

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RU 2 574 406 C2

Authors

Kurimura Muneaki

Taira Siniti

Tomojasu Takakhiro

Ito Nobuaki

Tai Kuninori

Takemura Noriaki

Matsuzaki Takajuki

Mendzo Jasukhiro

Mijamura Sin

Sakuraj Jokhdzi

Vatanabe Akikhito

Sakata Jasujo

Masumoto Takumi

Akazava Kokhej

Sugino Kharukhiko

Amada Naoki

Okhasi Satosi

Sinokhara Tomoiti

Sasaki Khirofumi

Morita Tisako

Jamasita Dzunko

Nakadzima Satoko

Dates

2016-02-10—Published

2006-05-12—Filed