PHARMACEUTICAL COMPOSITION FOR TREATING INFECTIOUS INFLAMMATORY DISEASES AND METHOD FOR PREPARING IT Russian patent published in 2013 - IPC A61K9/107 A61K31/7056 A61P1/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine and pharmaceutical industry, and concerns a combined pharmaceutical composition with antibacterial and antifungal activity. The composition comprises clindamycin phosphate, butoconazole nitrate as active ingredients. As a basis, the composition comprises a combination of a hydrophobic ingredient, a hydrophilic ingredient and an emulsifier and a gelling agent. A method of preparing the declared composition involves that a solution of clindamycin salt or ester in a part of the hydrophilic ingredient is added with the gelling polymer, then the emulsion prepared of a solution of butoconazole in the remained part of the hydrophilic ingredient, the hydrophobic ingredient and the emulsifier, and the prepared mixture is agitated until smooth.

EFFECT: new pharmaceutical composition is characterised by a high level of antibacterial and antifungal activity, stability both at the storage temperature (25°C), and at temperature of use (37°C), good packaging extrusion and high osmotic activity.

13 cl, 1 tbl, 4 ex