PHARMACEUTICAL COMPOSITION FOR TREATING VAGINAL CANDIDIASIS AND METHOD FOR PREPARING IT Russian patent published in 2015 - IPC A61K31/4174 A61K47/30 A61K47/00 A61K9/06 A61K9/107 A61J3/04 A61P31/10 

Abstract RU 2538703 C2

FIELD: medicine.

SUBSTANCE: as an active substance, the composition contains butoconazol, a base that is a combination of a hydrophobic ingredient, a hydrophilic ingredient and an emulsifier, and also a gel-forming polymer. Hydroxypropylstarch phosphate is preferentially used as the gel-forming polymer. A method for preparing the declared composition consists in the fact that a mixture of butoconazol with a portion of the hydrophilic ingredient, the hydrophobic ingredient and emulsifier is added with a dispersion of the gel-forming polymer in the rest of the hydrophilic ingredient; the produced mixture is agitated homogenously with a preserving agent added where it might be necessary.

EFFECT: new pharmaceutical composition is characterised by a high level of antifungal activity, stability both at a storage temperature, and at a use temperature, and good pack extrusion.

14 cl, 2 tbl, 10 ex

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Authors

Vaneshina Oksana Vladimirovna

Tarasova Ehlina Nikolaevna

Ljapunov Nikolaj Aleksandrovich

Bezuglaja Elena Petrovna

Goncharova Natal'Ja Viktorovna

Pit'Kin Andrej Sergeevich

Dates

2015-01-10Published

2013-03-12Filed