PHARMACEUTICAL FORMULATION FOR TREATING INFECTIOUS INFLAMMATORY GYNAECOLOGICAL DISORDERS AND METHOD FOR PREPARING IT Russian patent published in 2013 - IPC A61K31/7056 A61K47/36 A61K47/00 A61K9/06 A61J3/04 A61P31/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine and concerns a combined pharmaceutical composition having antibacterial activity. As an active substance, the composition contains a clindamycin salt or ester, a base which is a combination of a hydrophobic ingredient, a hydrophilic ingredient and an emulsifier, and a gelling polymer. A method of preparing the declared composition involves the fact that a solution of the clindamycin salt or ester in a part of the hydrophilic ingredient is added with the gelling polymer, then the emulsion prepared of a residual part of the hydrophilic ingredient, the hydrophobic ingredient and the emulsifier, and the prepared mixture is agitated until smooth.

EFFECT: new pharmaceutical formulation is characterised by a high level of antibacterial activity, stability both at storage temperature (25°C), and at temperature of use (37°C), good packaging extrusion.

15 cl, 1 dwg, 2 tbl, 4 ex