PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS Russian patent published in 2013 - IPC C07D417/04 C07D417/14 A61K31/4439 A61K31/506 A61P1/04 A61P3/04 A61P9/00 A61P11/00 A61P29/00 A61P35/00 

Abstract RU 2481346 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to compounds of formula I , wherein R2 means methyl, Y means carbon or nitrogen, and R1, R3 and R4 have the value specified in the patent claim. Also, the invention refers to a pharmaceutical composition for the use as a pharmaceutical drug having activity of a phosphatidylinositol-3-kinase inhibitor, to the use of the compounds of formula I for preparing the pharmaceutical drug for treating a disease mediated by phosphatidylinositol 3-kinase and to a method for preparing the compounds of formula I .

EFFECT: preparing the compounds of formula I possessing activity of the phosphatidylinositol-3-kinase inhibitor.

10 cl, 5 tbl, 51 ex

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RU 2 481 346 C2

Authors

Brjus Ajan

Kjunu Bernar

Keller Tomas Kh'Jugo

Pilgrim Gejnor Ehlizabet

Press Nikola

Le-Gran Darren Mark

Ritchi Kehti

Valade Barbara

Khejler Dzhudi

Badd Ehmma

Dates

2013-05-10Published

2004-04-30Filed