FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to a compound of formula
, or to a pharmaceutically acceptable salt of the compound Ia where X represents CH; Z represents N; Y represents C with -NH2 attached to Y; p is equal to 1, B represents a halogen atom; A represents the group 
, and D represents an unbranched lower alkyl. Also, the invention refers to a pharmaceutical composition based on the compound of formula la and to the application of the compound of formula la in preparing a drug.
EFFECT: there are prepared new quinoline derivatives effective in treating the retinal diseases of aetiology including A2E and/or lipofuscin accumulation in retinal tissues in a subject.
9 cl, 10 dwg, 2 tbl, 6 ex
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