ISOXAZOLO-PYRIDINE DERIVATIVES Russian patent published in 2013 - IPC C07D413/12 C07D413/14 C07D417/14 C07D487/04 C07D491/10 A61K31/4439 A61P25/28 

Abstract RU 2484091 C2

FIELD: chemistry.

SUBSTANCE: invention relates to isoxazole-pyridine derivatives of formula , where X; R1; R2, R3, R4, R5 and R6 are as described in claim 1 of the invention and a pharmaceutically acceptable salt thereof. The invention also relates to a medicinal agent for treating diseases associated with the binding site of the GABA A α5 receptor based on compounds of formula I and use of said compounds in preparing a medicinal agent.

EFFECT: novel compounds are active towards the binding site of said receptor and are useful in treating cognitive disorders such as Alzheimer's disease.

22 cl, 372 ex

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RU 2 484 091 C2

Authors

Bjuttel'Mann Bernd

Jakob-Roehtne Roland

Knust Khenner

Lukas Meht'Ju K.

Tomas Ehndrju

Dates

2013-06-10Published

2008-11-26Filed