FIELD: chemistry.
SUBSTANCE: invention relates to novel phenyl methanone derivatives of the formula I: 
where R1 denote -OR1, heterocycle such as morpholinyl, pyrrolidinyl, tetrahydropyranyl, phenyl, heteoaryl such as pyrazolyl, which are not substituted or substituted with C1-6alkyl, halogen; R1 denote C1-6alkyl, C1-6alkyl substituted with halogen, or denotes a -(CH2)0-saturated C3-6cycloalkyl; R2 denotes -S(O)2-C1-6alkyl, -S(O)2NH-C1-6alkyl, NO2 or CN; R3 denotes pyridinyl, substituted with C1-6alkyl, substituted with halogen, or phenyl which is not substituted or substituted with one to three substitutes selected from a group consisting of C1-6alkyl, C1-6alkoxy, CN, NO2, halogen, C1-6alkyl, substituted with halogen, C1-6alkoxy, substituted with halogen, phenyl, sulphonamide; X denotes -CH2-, -NH-, -CH2O- or -OCH2-; n denotes 1, 2; m denotes 1, 2; o denotes 1 or 1; and pharmaceutically acceptable acid addition salt thereof.
EFFECT: compounds have glycine reuptake inhibition which enables their use to prepare a pharmaceutical composition.
9 cl, 2 tbl, 40 ex
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