FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to psychiatry, and concerns treating schizophrenia. That is ensured by administering a composite solution of cytokines which is prepared by arteriovenous perfusion of porcine spleen by physiological saline at a flow rate of 30-40 ml/min followed by sterilisation filtration and cryo-preservation. The cytokine solution is administered by inhalations in the form of a fine aerosol by a nebuliser in a dose of 10 ml/administration. Depending on the patient's initial state and the distinctions/severity of the disease for the first 3-5 days, the preparation is administered every 8 hours, then for 5-10 days - 1-2 times a day with a frequency of administration to be reduced to 1 time/3 days for 3 months with underlying total withdrawal of psychotropic agents.
EFFECT: administration of the cytokine solution which has a pronounced immunomodulatory effect in the developed regimen enhances the clinical effectiveness in the schizophrenic patients that manifests itself in the form of a pronounced reduction of the psychopathology by the scale PANSS and an induction of sustained remission lasting more than 6 months.
1 ex, 2 tbl
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Authors
Dates
2013-06-20—Published
2011-09-21—Filed