FIELD: medicine, pharmaceutics.
SUBSTANCE: solid pharmaceutical composition applicable for oral administration contains 3-(1.H.-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrol-2,5-dione or a pharmaceutically acceptable salt thereof, and at least one lubricating agent in the amount of 2.5 to 12 wt %. The composition is presented in the form of a tablet. What is also described is a method for preparing and using the pharmaceutical compositions.
EFFECT: composition under the invention is non-adhesive and shows a low fragility less than 1 wt/wt %.
14 cl, 3 tbl, 3 ex
