FIELD: chemistry.
SUBSTANCE: invention relates to 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione salts in crystalline form, where said salts are formed with an acid selected from hydrochloric acid, maleic acid, malonic acid and methanesulphonic acid. The invention also relates to a method of producing said salts, a pharmaceutical composition containing said salts and a method of treating diseases or disorders mediated by T lymphocytes and/or PKC, which involves addition of said salts.
EFFECT: high stability.
10 cl, 2 ex
| Title |
Year |
Author |
Number |
| CRYSTALLINE MODIFICATIONS OF 3-(1H-INDOL-3-YL)-4-(4-METHYLPIPERAZIN-1-YL)QUINAZOLIN-4-YL)PYRROL-2,5-DIONE |
2007 |
- Karpinski P'Otr
- Monn'E Stefani
- Ndz'E Ehl'Jas
- Papoutsakis Dimitris
- Satton Pol Allen
|
RU2481341C2 |
| NONHYGROSCOPIC CRYSTALLINE 5-[(Z)-(5-FLUORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[(2S)-2-HYDROXY-3-MORPHOLIN-4-YLPROPYL]-2,4-DIMETHYL-1H-PYRROL-3-CARBOXAMIDE MALEATE SALT, PHARMACEUTICAL COMPOSITION AND METHOD FOR CANCER TREATMENT |
2004 |
- Blasko Andrej
- Tszin' Tsinvu
- Lu Tsjun'
- Morejdzhis Majkl Ehntoni
- Song Dong
- Vondervell Brenda S'Ju
|
RU2319702C2 |
| PHARMACEUTICAL COMBINATIONS |
2013 |
- Porter Dejl
- Emeri Kerolajn
- Tan Lutszyan
- Jerramilli-Rao Padmadzha
|
RU2674995C2 |
| SALTS OF 4-[2-[[5-METHYL-1-(2-NAPHTHALINYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE |
2010 |
- Kuberes-Altisent Marija Rosa
- Sola-Karandel' L'Juis
- Garsija-Kousejro Urko
|
RU2559325C2 |
| NOVEL SALT OF 3-[(3-{[4-(4-MORPHOLINYLMETHYL)-1H-PYRROL-2-YL]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOL-5-YL)METHYL]1,3-THIAZOLIDINE-2,4-DIONE, PREPARATION THEREOF AND FORMULATIONS CONTAINING SAME |
2014 |
- Le-Floik Aleksandr
- Gidotti Zherom
- Leteller Filipp
|
RU2680826C9 |
| PHARMACEUTICAL COMPOSITION |
2008 |
- Koshkhar Charu
- Deodkhar Unmesh
- Kerudi Aravind
- Babu G.V.M.
|
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| PYRAZINO[1,2-A]INDOLE COMPOUNDS, PREPARATION AND USE THEREOF IN MEDICAMENTS |
2014 |
- Merse-Vidal Ramon
- Dias Fernandes Khose Luis
- Almansa Rosales Karmen
|
RU2660417C2 |
| SALTS OF 1-(4-(2-((1-(3,4-DIFLUOROPHENYL)-1N-PYRAZOL-3-YL)METHOXY)ETHYL)PIPERAZIN-1-YL)ETHANONE |
2016 |
- Torrens-Jover Antoni
- Almansa Rosales Carmen
|
RU2727974C2 |
| DERIVATIVE OF 1-[(INDOLE-3-YL)CARBONYL]PIPERAZINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND ITS USING |
2003 |
- Kouli Fillip Martin
- Kolfild Uilson
- Tirni Dzhehjson
- Kehrns Dzhejms
- Adam-Uorrell Dzhulija
- Jork Mark
|
RU2318821C2 |
| SOLID FORMS OF 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS AND USE |
2012 |
- Myuller Dzhordzh V.
- Man Khon-Vakh
- Koen Bendzhamin M.
- Li In
- Syuj Dzhin
- Leong Uillyam V.
|
RU2611007C2 |
