LOCAL PHARMACEUTICAL ANTIBACTERIAL COMPOSITION OF ACTIVE BIOMETALLIC COMPLEXES Russian patent published in 2013 - IPC A61K31/4164 A61K31/455 A61K31/167 A61K47/06 A61P31/02 A61P17/02 

Abstract RU 2489147 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and may be used for treating septic wounds and burns. A composition possessing antibacterial action contains active metal biocomplexes with 5-nitroimidazole and β-pyridine carboxylic acid and a base providing a soft dosage form. As a gelling agent, there may be used modified cellulose derivatives, additionally comprising methyl monosilane hydrogel (enterosgel) and/or polyvinylpyrrolidone, or an alloy of polyethylene oxide-400 and polyethylene oxide-1500. As a mixture of hydrophilic substances, the base contains substances specified in a group of: polyethylene oxides, dimexide, glycerol and aerosol, may comprise at least one target additive of: anaesthetic - trimecaine, pyrromecaine, lidocaine, or a mixture thereof, a repair process stimulator - methyluracil, acemine, solcoseryl, Spirulina microalgae (Spirulina platensis), or a mixture thereof, antiseptic - miramistine, chlorhexidine digluconate, dioxidine or a mixture thereof. The composition is presented in the form of an ointment or gel.

EFFECT: invention provides the improved microcirculation in wound tissues, as well as anti-inflammatory action, repair process stimulation.

5 cl, 6 tbl, 4 ex

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RU 2 489 147 C2

Authors

Lazurina Ljudmila Petrovna

Lositskaja Olesja Sergeevna

Basareva Ol'Ga Il'Inichna

Bukreeva Ekaterina Mikhajlovna

Samokhvalova Irina Vjacheslavovna

Dates

2013-08-10Published

2011-08-31Filed