ANTIBACTERIAL AND NECROLYTIC EXTERNAL AND LOCAL LISOAMIDASE PHARMACEUTICAL COMPOSITION Russian patent published in 2009 - IPC A61K35/74 A61K38/43 A61K31/198 A61P17/02 

FIELD: medicine.

SUBSTANCE: pharmacological preparations are applied for treatment of purulent wounds and burns, pyoinflammatory dermatopathies, and for acceleration of healing and improvement of wound healing conditions. The external and local pharmaceutical composition possesses antibacterial and necrolytic action; it contains an active complex of bacteriolytic and proteolytic enzymes - Lisoamidase, a base and at least one desired additive chosen from: a substance disarranging the membrane structure of gram-negative microorganisms, an antibiotic, an anesthetic, a reparative process stimulator. The base is hydrophilic substances and a perfluororganic compound emulsion or their physiologically acceptable mixture or their physiologically comprehensible mix in certain component ratio.

EFFECT: enhanced therapeutic activity and ease of use, lower consumption of the active substance, ensured anaesthetising effect, additional stimulation of reparative processes, improved microcirculation, reduced secondary tissue necrosis surrounding a wound caused by excess free radical oxidation.

7 cl, 12 ex