FIELD: biotechnologies.
SUBSTANCE: population of Tr1 cells is identified, being aimed against food antigen from regular ration of a human being and having phenotype CD4+CD25-FoxP3- in idle condition. The produced population of Tr1 cells in a combination with one or several pharmaceutically acceptable carriers, or in a combination with one or more pharmaceutical agents, used to treat inflammatory bowel conditions and selected from a group including anti-TNF, natalizumab, anti-IL1, anti-IL-6, anti-IL-12, anti-IL-17 and anti-IL-23, analogues of antagonist of a receptor IL-1.5 aminosalicylic acid and its analogues, corticoids, probiotics, methotrexate, azathioprine, 6-mercaptopurine, thalidomide, leflunomide, used within pharmaceutical compositions for treatment of inflammatory bowel conditions.
EFFECT: invention makes it possible to produce an efficient agent for treatment of inflammatory bowel conditions.
15 cl, 8 dwg, 1 tbl, 2 ex
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Authors
Dates
2013-10-10—Published
2008-11-26—Filed