METHOD OF CHOOSING THERAPEUTIC APPROACH TO PSYCHOPHARMACOTHERAPY RESISTANT SCHIZOPHRENIA Russian patent published in 2013 - IPC A61N1/18 A61M21/00 A61K38/28 A61P25/18 G01N33/48 

Abstract RU 2495685 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely psychiatry, and may be used for choosing a therapeutic approach to psychopharmacotherapy resistant schizophrenia. For this purpose, after pharmacoresistance has been stated, total blood serotonine and daily dopamine excretion are examined. If observing the reduction of serotonin and standard or low dopamine excretion, a course of electric electroconvulsive therapy is applied. High dopamine excretion regardless of the serotonin content, a course of electric electroconvulsive therapy is applied. In the other cases, family psychotherapy is used. The patient is treated with underlying supporting psychopharmacotherapy. At the same time, electric electroconvulsive and insulin-comatose therapy is contraindicated in case of active, decompensated physical and neurological diseases.

EFFECT: method provides the higher clinical effectiveness in the treatment-resistant patients with individual pathogenic direction of the therapeutic effect.

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RU 2 495 685 C1

Authors

Soldatkin Viktor Aleksandrovich

Bukhanovskij Aleksandr Olimpievich

Tret'Jakov Andrej Vladimirovich

Bobkov Aleksej Semenovich

Perekhov Aleksej Jakovlevich

Mrykhin Vladimir Valer'Evich

Bukhanovskaja Ol'Ga Aleksandrovna

Kovalev Aleksandr Ivanovich

Dates

2013-10-20Published

2012-04-26Filed