METHOD OF DIAGNOSING AFFECTION OF PERIPHERAL NERVES IN LABORATORY ANIMALS IN REMOTE PERIOD OF EXPOSURE TO MERCURIC CHLORIDE Russian patent published in 2013 - IPC A61B5/488 G09B23/28 

Abstract RU 2497448 C1

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, in particular to experimental medicine. Stimulatory myography is performed to laboratory animals 9 weeks after exposure to toxicant is stopped. Amplitude of M-response (mV) and duration of M-response (ms) on median nerve are registered. Area of involvement of motor units is calculated. Calculation of canonic value is performed. Obtained results are compared with constant and if Cv is higher than 8.9, conclusion about absence of signs of chronic exposure to mercuric chloride is made, if Cv is lower or equals 8.9, affection of peripheral nerves in remote period of exposure to mercuric chloride is diagnosed.

EFFECT: method makes it possible to eliminate killing of animals and is simpler in implementation.

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RU 2 497 448 C1

Authors

Rusanova Dina Vladimirovna

Sosedova Larisa Mikhajlovna

Jakimova Natal'Ja Leonidovna

Dates

2013-11-10Published

2012-04-23Filed