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2 498 990

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IPC

C07F9/53(2006-01-01)

A61K31/66(2006-01-01)

A61P31/06(2006-01-01)

(21) (22)

Application

2012130752/04, 2012-07-17

(24)

Start date

2012-07-17

(22)

Actual filing date

2012-07-17

(45)

Published

2013-11-20

(72)

Inventor

Kostin Anton AlekseevichTatarinov Dmitrij Anatol'EvichKashapov Lenar RamilovichChestnova Regina Valer'EvnaValiev Ravil' ShamilovichGaraev Ramil SufiakhmetovichBuzykin Boris IvanovichMironov Vladimir Fedorovich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauki Institut Organicheskoj I Fizicheskoj Khimii Im. A.E. Arbuzova Kazanskogo Nauchnogo Tsentra Rossijskoj Akademii Nauk

DIALKYL(2-METHYL-4-OXOPENT-2-YL)PHOSPHINE OXIDE PYRIDINOYL HYDRAZONES, HAVING ANTITUBERCULOUS ACTIVITY Russian patent published in 2013 - IPC C07F9/53 A61K31/66 A61P31/06

Abstract RU 2498990 C1

FIELD: chemistry.

SUBSTANCE: invention relates to dialkyl(2-methyl-4-oxopent-2-yl) phosphine oxide pyridinoyl hydrazones (Ia-c) for treating tuberculosis, which can be used in medicine and veterinary: la Py-4-Py, R=Et; Ib Py=4-Py, R=Pr; 1c Py=3-Py, R=Et.

EFFECT: novel efficient antituberculous preparations with low toxicity, which do not exhibit neurotoxic activity.

2 cl, 3 ex, 2 tbl

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RU 2 498 990 C1

Authors

Kostin Anton Alekseevich

Tatarinov Dmitrij Anatol'Evich

Kashapov Lenar Ramilovich

Chestnova Regina Valer'Evna

Valiev Ravil' Shamilovich

Garaev Ramil Sufiakhmetovich

Buzykin Boris Ivanovich

Mironov Vladimir Fedorovich

Dates

2013-11-20—Published

2012-07-17—Filed