ANTIBODIES TO NKG2A AND THEIR APPLICATIONS Russian patent published in 2013 - IPC C07K16/28 A61K39/395 A61P31/12 A61P35/00 A61P37/00 C12N15/13 

Abstract RU 2499001 C2

FIELD: biotechnologies.

SUBSTANCE: invention proposes humanised anti-NKG2A antibody obtained from murine antibody Z270, which is characterised through amino-acid sequences of variable domains, and method of its obtainment. Besides, a pharmaceutical composition is described, which contains an antibody according to the invention, a treatment method and application of the antibody in production of a medicine to be injected into a patient who is a human being suffering the disorder chosen from cancer, virus disease, inflammatory disorder and autoimmune disorder.

EFFECT: invention can be further used in therapy.

14 cl, 20 dwg, 2 tbl, 16 ex

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RU 2 499 001 C2

Authors

Spe Petrus Jokhannes Lui

Padker Seren Berg

Dates

2013-11-20Published

2007-06-28Filed