FIELD: biotechnologies.
SUBSTANCE: invention proposes humanised anti-NKG2A antibody obtained from murine antibody Z270, which is characterised through amino-acid sequences of variable domains, and method of its obtainment. Besides, a pharmaceutical composition is described, which contains an antibody according to the invention, a treatment method and application of the antibody in production of a medicine to be injected into a patient who is a human being suffering the disorder chosen from cancer, virus disease, inflammatory disorder and autoimmune disorder.
EFFECT: invention can be further used in therapy.
14 cl, 20 dwg, 2 tbl, 16 ex
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Authors
Dates
2013-11-20—Published
2007-06-28—Filed