FIELD: medicine.
SUBSTANCE: claimed invention relates to biotechnology. Claimed is a monoclonal antibody, which specifically binds with the second Kunitz domain of a tissue factor pathway inhibitor (TFPI), which is characterised by the fact that it contains 6CDR. Described are: cell, expressing the said antibody, and the application of the antibody for the treatment of a subject with coagulopathy.
EFFECT: application of the invention makes it possible to provide novel antibodies, which can be applied in therapy for the reduction of the blood coagulation time.
6 cl, 24 dwg, 12 tbl, 16 ex
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Authors
Dates
2015-09-10—Published
2009-12-18—Filed