STABILISATION OF DEHYDROGENASES WITH STABLE COFERMENTS Russian patent published in 2013 - IPC C12N9/96 C12N9/06 C12Q1/32 

Abstract RU 2499834 C2

FIELD: biotechnologies.

SUBSTANCE: stabilisation method of a ferment representing dehydrogenase is proposed. Ferment is kept in presence of stable coferment chosen from stable derivatives of nicotine amide adenine dinucleotide (NAD/NADH) or compounds of nicotine amide adenine dinucleotide phosphate (NADP/NADPH), or shortened derivatives of NAD, or compound (I) presented in the formula. Besides, a ferment stabilised with stable coferment and a detector reagent containing it are proposed. The invention also refers to a test element containing the stabilised ferment or the detector reagent for detection of analysed substance.

EFFECT: invention allows keeping the stabilised ferment without a drying reagent at low temperature or at high relative humidity; ferment activity under those conditions is decreased in comparison to the initial level.

22 cl, 28 dwg, 4 ex

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RU 2 499 834 C2

Authors

Khajndl' Diter

Khorn Karina

Gessler-Diche Klaudia

Khenes Joakhim

Dates

2013-11-27Published

2009-02-19Filed