COMPOUNDS AND METHODS FOR URIC ACID REDUCTION Russian patent published in 2013 - IPC A61K31/03 A61K31/85 A61K31/192 A61P19/06 

Abstract RU 2501555 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a method for reducing the blood uric acid concentration in a mammal patient, or increasing the uric acid discharge in a mammal patient involving administering 2-(3-(2,6-dimethylbenzyloxy)-4-methylphenyl)acetic acid or a pharmaceutically acceptable salt thereof in the effective amount into the patient. Besides, the declared invention is used in a method of treating or preventing a number of conditions, including uratic arthritis, hyperuricemia, the uric acid levels exceeding those normally diagnosed as hyperuricemia, renal dysfunction, renal calculi, cardiovascular disorder, risk of cardiovascular disorder, tumour lysis syndrome and cognitive impairment.

EFFECT: declared compounds may be used for preparing the pharmaceutical composition.

11 cl, 6 dwg, 13 tbl, 28 ex

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RU 2 501 555 C2

Authors

O'Nejl Dzhejms Dennen

Bamat Majkl K.

Von Borstel Rejd V.

Sharma Shalini

Arudchandran Ramachandran

Dates

2013-12-20Published

2009-03-13Filed