METHOD FOR SIMULATING IMMUNE-DEPENDENT ALLOGENIC PREGNANCY LOSS IN LABORATORY MICE Russian patent published in 2014 - IPC G09B23/28 

Abstract RU 2511107 C1

FIELD: medicine.

SUBSTANCE: method involves an intraperitoneal administration of N-acetyl-β-1-O-heptylmuramyl-L-alanyl-D-isoglutamine 20 mcg in 0.9% NaCl 0.1 ml per female laboratory mouse. The preparation is administered on the 5th day of pregnancy in a period of blastocyst implantation and on the 7th day in the beginning of a placentation period.

EFFECT: high level of embryo resorption, high model reproducibility and applicability of linear and non-linear animals.

3 ex, 3 tbl

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RU 2 511 107 C1

Authors

Artem'Eva Ksenija Aleksandrovna

Boltovskaja Marina Nikolaevna

Kaljuzhin Oleg Vital'Evich

Stepanova Irina Il'Darovna

Jaglova Natal'Ja Valentinovna

Dates

2014-04-10Published

2012-12-26Filed