METHOD OF OBTAINING GLYCOLIDE Russian patent published in 2014 - IPC C07D319/12 

FIELD: chemistry.

SUBSTANCE: solution of 65% glycolic acid is placed in evaporation flask of thin-film rotary evaporator with constant supply of nitrogen (0.5 l/min) with 0.3-0.5 wt % catalyst (ZnO), is heated from 120°C to 185°C under pressure 150-300 mmHg, with the following cooling of obtained distillate in refrigerator by water and condensation and cooling of reaction mass of oligomer of glycolic acid and addition of 0.5-1.5 wt % of catalyst (Sb₂O₃), placement of obtained mixture in device for distillation in vacuum at temperature 270-280°C. Process of water distillation is realised for 3-4 hours in thin-film rotatory evaporator.

EFFECT: wide application in medicine, production of biodegradable materials for products packing, package materials, disposable products.

1 dwg, 1 ex