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2 517 061

(13)

(51)

IPC

A61K31/203(2006-01-01)

A61K31/355(2006-01-01)

A61K31/375(2006-01-01)

A61K31/5375(2006-01-01)

A61K33/04(2006-01-01)

A61K33/30(2006-01-01)

A61K38/48(2006-01-01)

A61K36/00(2006-01-01)

A61P15/08(2006-01-01)

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Application

2012153840/15, 2012-12-13

(24)

Start date

2012-12-13

(22)

Actual filing date

2012-12-13

(45)

Published

2014-05-27

(72)

Inventor

Bozhedomov Vladimir AleksandrovichNikolaeva Marina Arkad'EvnaLipatova Natal'Ja AlekseevnaUshakova Irina VjacheslavovnaSporish Evgenij AndreevichRokhlikov Igor' MikhajlovichSukhikh Gennadij Tikhonovich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Tsentr Akusherstva, Ginekologii I Perinatologii Imeni Akademika V.I. Kulakova Ministerstva Zdravookhranenija Rossijskoj Federatsii

METHOD OF TREATING MALE STERILITY CAUSED BY AUTOIMMUNE RESPONSE TO SPERM CELLS Russian patent published in 2014 - IPC A61K31/203 A61K31/355 A61K31/375 A61K31/5375 A61K33/04 A61K33/30 A61K38/48 A61K36/00 A61P15/08

Abstract RU 2517061 C1

FIELD: medicine.

SUBSTANCE: there are used chymotrypsin 360-480 mg/day, trypsin 360-480 mg/day, papaine 900-1200 mg/day and 1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one (Inosine) 1200-1800 mg/day, zinc 7-10 mg/day, selenium 50-100 mcg/day, vitamin E - 30-400 mg/day, C - 180-500 mg/day, B-carotin - 4-10 mg/day taken orally for 2-3 weeks during a female's follicular phase.

EFFECT: method enables reducing the binding of sperm-coating antibodies to sperm cells and improving the quantitative measures of the semen analysis through the complex immunomodulatory, proteolytic, inflammatory, antioxidant, antihypoxic and anabolic effects.

1 ex, 1 tbl

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RU 2 517 061 C1

Authors

Bozhedomov Vladimir Aleksandrovich

Nikolaeva Marina Arkad'Evna

Lipatova Natal'Ja Alekseevna

Ushakova Irina Vjacheslavovna

Sporish Evgenij Andreevich

Rokhlikov Igor' Mikhajlovich

Sukhikh Gennadij Tikhonovich

Dates

2014-05-27—Published

2012-12-13—Filed