1-[4-[1-(4-CYCLOHEXYL-3-TRIFLUOROMETHYLBENZYLOXYIMINO)ETHYL]-2-ETHYL BENZYL]AZETIDINE-3-CARBOXYLIC ACID HEMIFUMARATE SALT Russian patent published in 2014 - IPC C07D205/04 A61K31/397 A61P35/00 A61P37/00 

Abstract RU 2518114 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino]ethyl}-2-ethyl benzyl)azetidine-3-carboxylic acid hemifumarate salt, as well as to its polymorphous forms, pharmaceutical compositions inhibiting EDG receptors containing the above salt and its polymorphs.

EFFECT: what is prepared is the novel 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino]ethyl}-2-ethyl benzyl)azetidine-3-carboxylic acid salt and the based pharmaceutical composition that can find application in treating the lymphocyte-mediated conditions.

22 cl, 9 dwg, 3 tbl, 6 ex

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RU 2 518 114 C2

Authors

Lekh Tsizhevski

Mehrilin De-La-Krus

P'Otr Kh. Karpinski

Mikhaehl' Mutts

Kristian Riger

Kaspar Fogel'

Rikardo Shneberger

Dates

2014-06-10Published

2009-12-16Filed