SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS AND USING THEM FOR TREATING MUSCULAR TISSUE INFLAMMATION Russian patent published in 2014 - IPC A61K31/397 A61P21/00 

Abstract RU 2521286 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is presented is a group of inventions involving using 1-{4-[1-(4-cyclohexyl-3-trifluoromethylbenzyloxyimino)ethyl]-2-benzylethyl}azetidine-3-carboxylic acid, its N-oxide, or a mixture of isomers, its salts, solvates or hydrates for preparing a drug for preventing, inhibiting or treating an inflammatory condition specified in polymyosite and dermatopolymyosite (versions), a related method of treating, and a pharmaceutical composition for the same application containing the above compound.

EFFECT: what has been shown is an almost complete block of cytokine-induced amyotrophia.

4 cl, 2 dwg

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RU 2 521 286 C2

Authors

Sajid Sokhajl Akhmed

Marko Londej

Timoti Rajt

Peter Gergeli

Dates

2014-06-27Published

2009-07-22Filed