FIELD: chemistry.
SUBSTANCE: invention relates to crystalline 1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)-ethyl]-3-(2-methylquinolin-4-yl)-urea of formula I
,
in monosulphate trihydrate form. The invention also relates to a composition based on the said compound which has antagonistic effect on urotensin.
EFFECT: obtaining a novel compound and compositions based on said compound, which can be used in medicine as neurohormonal antagonists.
8 cl, 3 dwg, 5 tbl, 5 ex
| Title |
Year |
Author |
Number |
| CRYSTALLINE FORMS OF 1-((2R,4R)-2-(1H-BENZO[D]IMIDAZOL-2-YL)-1-METHYLPIPERIDIN-4-YL)-3-(4-CYANOPHENYL)UREA MALEATE |
2016 |
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|
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|
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2005 |
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|
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|
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2010 |
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|
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2013 |
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|
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2009 |
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2012 |
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- Brekelmann Martin
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|
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|
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2012 |
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RU2625305C2 |
