1-[2-(4-BENZYL-4-HYDROXYPIPERIDIN-1-YL)-ETHYL]-3-(2-METHYLQUINOLIN-4-YL)-UREA IN CRYSTALLINE SULPHATE FORM Russian patent published in 2010 - IPC C07D401/12 A61K31/4709 A61P9/02

Abstract RU 2397978 C2

FIELD: chemistry.

SUBSTANCE: invention relates to crystalline 1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)-ethyl]-3-(2-methylquinolin-4-yl)-urea of formula I

in monosulphate trihydrate form. The invention also relates to a composition based on the said compound which has antagonistic effect on urotensin.

EFFECT: obtaining a novel compound and compositions based on said compound, which can be used in medicine as neurohormonal antagonists.

8 cl, 3 dwg, 5 tbl, 5 ex

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RU 2 397 978 C2

Authors

Rede Stefan

Bukhmann Shtefan

Bonar Zhan-Mishel'

Vuane Bertran

Dates

2010-08-27—Published

2005-10-11—Filed