COMBINATIONS CONTAINING ANTIMUSCARINE AGENTS AND CORTICOSTEROIDS Russian patent published in 2010 - IPC A61K31/439 A61K45/06 A61K31/573 A61K31/58 A61P11/06 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention concerns drugs and covers a combination applicable for treating a respiratory disease representing asthma, acute or chronic bronchitis, emphysema, chronic obstructive pulmonary disease, bronchial hyperactivity or rhinitis, containing effective amount of (a) corticosteroid and effective amount of (b) M3 muscarine receptors antagonist which represents 3(R)-(2-hydroxy-2,2-dithiene-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane in the form of salt containing anion X which is pharmaceutically acceptable anion of mono-or polyvalent acid. There is also disclosed application of 3(R)-(2-hydroxy-2,2-dithiene-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane and corticosteroid for preparing a drug for treating a respiratory disease and the method of treating said respiratory disease.

EFFECT: combinations under the invention provide improved therapeutic effect in treating the respiratory diseases.

21 cl, 1 dwg, 1 tbl, 7 ex