CORTICOSTEROID-CONTAINING ORALLY DISINTEGRATING TABLET COMPOSITIONS FOR TREATING EOSINOPHILIC ESOPHAGITIS Russian patent published in 2019 - IPC A61K31/56 A61P1/00 A61K9/20 A61K9/16 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to the pharmaceutical industry, in particular to an orally disintegrating tablet comprising corticosteroids for the treatment of inflammatory conditions of the upper part of the gastrointestinal tract. Orally disintegrating tablet for oral administration for the treatment of inflammatory conditions of the upper gastrointestinal tract, comprising: a topically active corticosteroid or its pharmaceutically acceptable salt, ester or polymorphic modification adsorbed on a pharmaceutically acceptable carrier; rapidly dispersing microgranules. Method for the treatment of inflammatory pathological conditions of the gastrointestinal tract. Method of obtaining orally disintegrating tablets.

EFFECT: disclosed orally disintegrating tablet comprising corticosteroids for treating an inflammatory pathological condition of the gastrointestinal tract obtained by the disclosed method reduces the side effects of systemic absorption and improves the therapeutic efficacy of corticosteroids.

45 cl, 1 dwg, 12 tbl, 15 ex