FIELD: chemistry.
SUBSTANCE: invention relates to method of obtaining 3-Z-[1-(4-(N-((4-methylpiperazin-1-yl)methylcarbonyl)-N-methylamino)-anilino)-1-phenylmethylene]-6-methoxycarbonyl-2-indolinone of formula including stage of reaction of compound of formula, , obtained by dechloroactilation of compound of formula catalysed by base, with compound of formula .
EFFECT: method makes it possible to increase output of 3-Z-[1-(4-(N-((4-methylpiperazin-1-yl)methylcarbonyl)-N-methylamino)-anilino)-1-phenylmethylene]-6-methoxycarbonyl-2-indolinone.
8 cl, 8 ex
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Authors
Dates
2014-08-10—Published
2008-12-02—Filed