NEW PEPTIDE AND ITS APPLICATION Russian patent published in 2014 - IPC C07K7/06 A61K38/08 A61P19/02 

Abstract RU 2525913 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a peptide represented by the formula (I) X1-Leu-X2-Leu-X3, where X1 is Glu or Asp, X2 is His, Lys or Arg, X3 is Asp or Glu, at that Glu, Asp, Leu, His, Lys and Arg, or its pharmaceutically acceptable salt and its compositions for treatment or prevention of cartilage damage and/or arthritis.

EFFECT: proposed peptide can affect the regeneration of cartilage tissue, inhibition of expression of the enzyme causing cartilage tissue matrix degradation, or inhibition of chondrosteosis.

7 cl, 2 tbl, 11 dwg, 15 ex

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RU 2 525 913 C1

Authors

Kim Hae Jin

Lee Je Wook

Kwon Young Joon

Moon Eun Joung

Dates

2014-08-20Published

2011-06-22Filed