FIELD: medicine; pharmaceutics.
SUBSTANCE: invention relates to the use of a mesenchymal stem cell expressing the TSG-6 protein in the preparation of a pharmaceutical composition for cartilage regeneration, where the mesenchymal stem cell expressing the TSG-6 protein is a recombinant mesenchymal stem cell comprising one or more selected from the group consisting of a gene encoding a TSG-6 protein, and a recombinant vector containing a gene encoding a TSG-6 protein.
EFFECT: higher expression of collagen II protein, improved cartilage structure, anti-inflammatory action, treatment of osteoarthritis.
4 cl, 11 dwg, 8 tbl, 5 ex
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