FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to veterinary virology and biotechnology and concerns a type A foot-and-mouth disease vaccine. The vaccine contains an avirulent and purified antigen material of the viral strain Aphtae epizooticae, of the family Picornaviridae, of the genus Aphtovirus, of the serotype A, deposited in the collection of FGU VGNKI (Federal State Institution Russian National Centre for Quality and Standartisation of Drugs and Feed for Animals), registration No. 2045/Kirghizia/2007-DEPA No. 2045/Kirghizia/2007-DEP prepared in a passaged cell culture VNK-21, representing s suspension containing preferentially the immunogenic viral components 146S and 75S of foot-and-mouth disease, the adjuvants aluminium hydroxide with saponin and a supporting medium in effective proportions.
EFFECT: vaccine possesses high immunogenicity and is able to provide the effective protection against a foot-and-mouth disease agent circulating in the countries of Transcaucasus, Central Asia, Near and Far East.
12 cl, 14 tbl, 1 dwg, 4 ex
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RU2560268C1 |
STRAIN OF FMD VIRUS Aphtae epizooticae OF TYPE A FOR CONTROLLING ANTIGENIC AND IMMUNOGENIC ACTIVITY AND FOR PRODUCTION OF BIOLOGICAL PREPARATIONS FOR DIAGNOSTICS AND SPECIFIC PROPHYLAXIS OF FMD OF TYPE A | 2014 |
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Authors
Dates
2014-08-27—Published
2012-08-09—Filed