SALTS OF ISOPHOSPHORAMIDE YPRITE AND ITS ANALOGUES Russian patent published in 2014 - IPC A61K31/664 A61P35/00 C07F9/22 

Abstract RU 2527531 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a crystalline compound effective for treating hyperproliferative diseases and having formula (I) ,

wherein A+ represents a conjugated acid of tris(hydroxymethyl)aminomethane (Tris); X and Y independently represent chlorine having a fusion point of 103.37°C-105.77°C, and an X-ray powder diffraction spectrum is presented in Fig. 2, as well as to using it for treating various oncological diseases.

EFFECT: what is presented is a new crystalline compound possessing high stability, effective for treating hyperproliferative diseases.

15 cl, 32 dwg, 2 tbl, 16 ex

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RU 2 527 531 C2

Authors

Amedio Dzhon S

Uollner Barbara P

Komarnitski Filipp B

Dates

2014-09-10Published

2008-04-04Filed