AGENT FOR TREATING SEPTIC WOUNDS, METHOD FOR PREPARING IT AND METHOD OF TREATING SEPTIC WOUNDS Russian patent published in 2014 - IPC A61K31/409 A61P17/02 

FIELD: medicine.

SUBSTANCE: biocompatible polymer representing a mixture of Pluronic F127 and carboxymethyl cellulose sodium salt is immobilised on hydroxyapatite nanoparticles. The agent represents the following mixture ratio, wt %: dimethylglucamine salt of chlorine E6 - 0.03-0.45; hydroxyapatite - 0.1-0.3; Pluronic F127 - 2.0-2.5; carboxymethyl cellulose sodium salt - 2.0-2.5; water - the rest. What is also presented is a method of preparing the above agent by immobilising the biocompatible polymer with an included dimethylglucamine salt of chlorine E6 on hydroxyapatite nanoparticles, involving mixing in water of Pluronic F127 with dimethylglucamine salt of chlorine E6, agitating the prepared mixture and solution for 30-40 min and adding carboxymethyl cellulose sodium salt. What is also presented is a method of treating septic wounds of soft tissues combining conventional treatment according to a standard practice and photodynamic therapy. The photodynamic therapy involves coating a wound surface with the presented agent in an amount of 0.05-0.1 g per 1 cm² of the wound surface, settling for 40-60 min; with the agent coating kept on, the wound surface is exposed to a low-intensity laser light at a wavelength of 663±0.03 nm, power density 1 Wt/cm² and energy density 25-30 J/cm².

EFFECT: invention provides the high clinical effectiveness.

8 cl, 2 dwg, 7 ex