CEFDINIR ACID SALT AND METHOD OF OBTAINING THEREOF Russian patent published in 2014 - IPC C07D501/22 A61K31/546 A61P31/04 

FIELD: chemistry.

SUBSTANCE: invention relates to a cefdinir acid salt, represented by formula I, where M represents Na⁺, K⁺, NH4⁺, or Cs⁺; Y represents SO₄ ^2- or PO₄ ^3-, and 1) if Y represents SO₄ ^2-: if m=1, then n=1; if m=0.5, then n=1.5; and 2) if Y represents PO₄ ^3-: if m=1, then n=2. Also claimed is a method of obtaining the cefdinir acid salt of formula (I), including preparation of a homogeneous mixture of cefdinir with a solvent, drop introduction into the homogenous mixture of cefdinir of a solution with an equimolar quantity of acid from the group: sulphuric acid, phosphoric acid, with further addition to the obtained transparent solution of an ammonium compound from the group: ammonium acetate, ammonium propionate, gaseous ammonia, aqueous ammonia solution, or with further addition to the obtained transparent solution of a compound of alkali metal from the group: sodium, potassium, cesium; or into the homogenous cefdinir mixture introduced by drop introduction is an equimolar amount of ammonium hydrosulphate or hydrosulphate of alkali metal from the group: sodium, potassium, or ammonium dihydrophosphate or alkali dihydrophosphate of alkali metal from the group: sodium, potassium, after which the obtained product of reaction, taking place for 15 minutes, is concentrated, crystallised, filtered and dried. In case, if acid or the compound contains a sulphate group, the obtained product is cefdinir acid salt, and if acid or the compound contains a phosphate group, the obtained product is cefdinir phosphate salt.

EFFECT: cefdinir acid salt, possessing high solubility.

8 cl, 2 tbl, 48 ex