FIELD: chemical or physical processes.
SUBSTANCE: present invention relates to a method of producing a long-chain cyclohexenone alcohol represented by formula I, where A is C10-18alkylene, R1, R2 and R3 are each independently methyl, and the method includes the following steps: (1a) a condensation reaction of a crude product of a long-chain cyclohexenone III and hydrazine or derivative thereof R4NHNH2, where R4 is
or
, R5 is 4-methylphenyl or amino, to obtain compound II, and (1b) hydrolysis of compound II in the presence of an acidic substance to obtain compound I
.
Invention also relates to intermediate compounds and use thereof for producing a compound of formula I.
EFFECT: present invention enables to obtain alcohol of formula I of high degree of purity.
22 cl, 2 tbl, 32 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PRODUCING METHOD OF LONG-CHAIN ALCOHOL OF HIGH PURITY CYCLOHEXENONE | 2017 |
|
RU2745062C2 |
| NOVEL POLYUNSATURATED COMPOUNDS, METHOD OF THEIR OBTAINING AND COMPOSITIONS WHICH CONTAIN THEM | 2006 |
|
RU2466988C2 |
| IONONE-BASED VANILLOID VRI RECEPTOR ANTAGONISTS | 2007 |
|
RU2447064C2 |
| METHOD FOR PREPARING RETINAL OR ADDUCT (COMPLETE-E)-RETINAL WITH HYDROQUINONE AND INTERMEDIATE SUBSTANCES | 2002 |
|
RU2318805C2 |
| RETINOIDS AND RETINOID-CONTAINING PHARMACEUTICAL COMPOSITION | 1997 |
|
RU2173683C2 |
| RETINOID | 1996 |
|
RU2166499C2 |
| METHOD OF PRODUCING POLYENE ALDEHYDES | 0 |
|
SU1493099A3 |
| HERBICIDIC AGENT | 0 |
|
SU1757439A3 |
| CYCLOPAMINE ANALOGUES | 2007 |
|
RU2486194C2 |
| FAMILY OF ARYL, HETEROARYL, O-ARYL AND O-HETEROARYL CARBASUGARS | 2012 |
|
RU2603769C2 |
Authors
Dates
2020-08-05—Published
2017-01-22—Filed