DERIVATIVES OF BENZAZEPINE AND BENZOTHIAZEPINE Russian patent published in 1997 - IPC

Abstract RU 2090562 C1

FIELD: organic chemistry. SUBSTANCE: product: derivatives of benzazepine and benzothiazepine of the formula (I): , or their pharmaceutically acceptable salts where: R1 - lower alkoxy, OH, lower alkanoyloxy, OCONY8Y9; X - CH2 or S. If X - CH2 then R2 means and others; if X - S then R2 means and others; R3 - lower alkoxy and others; R4 - lower alkoxy and others. Reagent 1: compound of the formula (I) where: R2 means H. Reagent 2: base. Reaction conditions: in inert solvent followed by treatment with compound of the formula R2-L where L - splitting off group. Synthesized compounds can be used in medicine since they show vasodilator activity. EFFECT: improved method of synthesis. 37 cl

Similar patents RU2090562C1

Title Year Author Number
METHOD OF SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS 1990
  • Dehvid M.Flojd[Us]
  • Dzhon T.Khant[Us]
  • Spenser D.Kimboll[Us]
  • Dzhon Krehpcho[Us]
  • Dzhagabandkhu Das[Us]
  • Dzhordzh S.Rovnjak[Us]
  • Dzhoel S.Barrish[Us]
RU2026296C1
PURINYL- OR PYRIMIDINYL-DERIVATIVES OF METHYLENECYCLOPENTYL 1991
  • Robert Zakhler[Us]
  • Vil'Jam A.Slusarchuk[Us]
RU2037496C1
7-OXABICYCLOHEPTYL-SUBSTITUTED HETEROCYCLIC AMIDES OR STEREOISOMERS THEREOF AS THROMBOXANE RECEPTOR ANTAGONISTS 1991
  • Filip M.Sher[Us]
  • Filip D.Stejn[Us]
  • Dehvid Flojd[Us]
  • Stiven E.Kholl[Us]
RU2015980C1
PROCESS FOR PREPARING BIS(HYDROXYMETHYL)CYCLOBUTYL PURINES OR PYRIMIDINES 1989
  • Uil'Jam A.Slusarchik[Us]
  • Robert Zakhler[Us]
RU2041213C1
HETEROCYCLIC NITROGEN-CONTAINING DERIVATIVES OF CARBOXYLIC ACID, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION 1993
  • Donal'D Sjukaranevskij
  • Dzhoel S.Behrrish
  • Ehdvard V.Patrillo
  • Dzheffri A.Robl
  • Denis I.Riono
RU2124503C1
IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION 1991
  • Majkl A.Poss[Us]
RU2111208C1
BIPHENYL-SUBSTITUTED DERIVATIVES OF QUINOLINE, A PHARMACEUTICAL COMPOSITION, A METHOD OF INHIBITION 1993
  • Denis Ehvan Riono
  • Dzhon Llojd
RU2122540C1
METHOD OF SYNTHESIS OF PYRANYL-CYANOGUANIDINE DERIVATIVES 1990
  • Karnail Atval[In]
  • Gari Dzhejms Grover[Us]
  • Kiong Sun Kim[Kr]
RU2057129C1
SULFUR-SUBSTITUTED MEVINIC ACID DERIVATIVES AND PROCESS FOR PREPARING THEREOF 1991
  • Ravi K.Varma[Us]
  • Dzheffri O.Saunders[Us]
  • Sehm T.Chao[Us]
  • Ehrik M.Gordon[Us]
  • Dinos P.Santafianos[Us]
RU2041205C1
METHOD OF SYNTHESIS OF TRIFLUOROMETHYLMERCAPTAN DERIVATIVES 1991
  • Norma Dzh.Delani[Us]
  • Dzhordzh S.Rovnjak[Us]
  • Melani Luts[Us]
RU2024504C1

RU 2 090 562 C1

Authors

Dehvid M.Flojd[Us]

Dzhon T.Khant[Us]

Spenser D.Kimboll[Us]

Dzhon Krehpcho[Us]

Dzhagabandkhu Das[Us]

Dzhordzh S.Rovnjak[Us]

Dzhoel S.Barrish[Us]

Dates

1997-09-20Published

1989-05-23Filed