FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to immunology. There are presented versions of human or cynomolgus monkey NR10 antibodies, including the humanised ones. There are described a method of treating or preventing an inflammatory disease mediated by IL-31 overexpression, and a method for producing the NR10 antibody having neutralising activity with using the above antibodies, as well as: using the antibody for preparing a therapeutic agent for the inflammatory disease mediated by IL-31 overexpression.
EFFECT: using the invention provides the human or cynomolgus monkey NR10 antibody having NR10 neutralising activity that can find application in medicine both for treating the inflammatory diseases related to NR10 overexpression, and for producing a drug for these diseases.
8 cl, 29 dwg, 19 tbl, 23 ex
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Authors
Dates
2014-10-20—Published
2008-12-05—Filed