NR10 ANTIBODY AND USING IT Russian patent published in 2014 - IPC C07K16/28 A61K39/395 A61P37/00 C12P21/00 

Abstract RU 2531521 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to immunology. There are presented versions of human or cynomolgus monkey NR10 antibodies, including the humanised ones. There are described a method of treating or preventing an inflammatory disease mediated by IL-31 overexpression, and a method for producing the NR10 antibody having neutralising activity with using the above antibodies, as well as: using the antibody for preparing a therapeutic agent for the inflammatory disease mediated by IL-31 overexpression.

EFFECT: using the invention provides the human or cynomolgus monkey NR10 antibody having NR10 neutralising activity that can find application in medicine both for treating the inflammatory diseases related to NR10 overexpression, and for producing a drug for these diseases.

8 cl, 29 dwg, 19 tbl, 23 ex

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Authors

Kuramoti,Taiti

Kasutani,Kejko

Okhiama,Soukhei

Tsunoda,Khirojuki

Igava,Tomojuki

Tatibana,Tatsukhiko

Siraiva,Khirotake

Esaki,Keiko

Dates

2014-10-20Published

2008-12-05Filed