HUMAN INTERLEUKIN-13 ANTIBODIES AND THEIR APPLICATION Russian patent published in 2011 - IPC C07K16/24 C12N15/13 C12N15/63 C12Q1/68 A61K39/395 A61P11/00 A61P43/00 

Abstract RU 2427589 C2

FIELD: medicine.

SUBSTANCE: there are offered versions of antibodies and their antigen-binding IL-13, particularly human IL-13 specific fragments. There are described: a pharmaceutical composition, a pharmaceutical compound of the antibody, versions of coding and hybridising nucleic acids and expression vectors. There are offered versions of: cells and methods of producing the antibody, methods of treating IL-13 associated disorders. A method of IL-13 detection in a sample is described.

EFFECT: use of the invention provides new IL-13 antibodies with KD about 10-10 M which can be used for diagnosing, preventing or treating one or more IL-13 associated diseases.

87 cl, 37 dwg, 5 tbl, 6 ex

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Authors

Kasaian Marion T.

Chistjakova Ljudmila

Veldman Geertruda M.

Markett Kimberli Ehnn

Tan Ksiang-Jang

Donaldson Debora D.

Lin Lora Long

Shehjn Tanja

Tam Ehmmi Szepui

Fejfant Ehrik

Vud Nehnsi L.

Fitts Lori Dzh.

Vidom Angela M.

Parris Kevin D.

Goldman Samuel Dzh.

Dates

2011-08-27Published

2005-06-09Filed