Show metadata Hide metadata

(19)

(11)

2 531 548

(13)

(51)

IPC

A61K39/395(2006-01-01)

A61P19/02(2006-01-01)

A61P37/02(2006-01-01)

C07K16/28(2006-01-01)

C12N15/13(2006-01-01)

(21) (22)

Application

2011117293/10, 2009-08-31

(24)

Start date

2009-08-31

(22)

Actual filing date

2009-08-31

(45)

Published

2014-10-20

(72)

Inventor

Osterrot FrankAjgner Zil'KeUehrek KristofVartenberg-Demand AndreaRudnev AnatolijZol'Dan Mikhaehl'Brjukher KristofDelken BenzhaminTsuber Shantal'Shul'Ts GregorChelot Niklas

(73)

Holder

Biotest Ag

COMPOSITION FOR TREATING DISEASE Russian patent published in 2014 - IPC A61K39/395 A61P19/02 A61P37/02 C07K16/28 C12N15/13

Abstract RU 2531548 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to biotechnology and represents a pharmaceutical composition applicable for treating a rheumatic disease and containing the humanised anti-CD4 antibody able to activate CD4+CD25+ regulatory T-cells, and methotrexat. The present invention also discloses a kit and a method of treating the rheumatic disease with using the above pharmaceutical combination and the above kit.

EFFECT: invention enables implementing more effective methods of treating the rheumatic diseases, including rheumatoid arthritis.

57 cl, 8 dwg, 2 tbl, 2 ex

Similar patents RU2531548C2

Title	Year	Author	Number
METHOD OF TREATING AUTOIMMUNE DISEASE (VERSIONS)	2009	Osterrot, Frank Ajgner, Zil'Ke Germer, Mattias Uehrek, Kristof Kraus, Ehl'Mar Vartenberg-Demand, Andrea Vol'F, Daniehle Kajzer, Zibille Lindner, Jurgen Brjukher, Kristof Delken, Benzhamin	RU2539110C2
AGENT FOR DISEASE TREATMENT	2009	Ajgner Zil'Ke Germer Mattias Osterrot Frank Uehrek Kristof Kraus Ehl'Mar Vartenberg-Demand Andrea Vol'F Daniehle Kajzer Zibille Lindner Jurgen Brjukher Kristof Delken Benzhamin	RU2540018C2
AGENT FOR TREATING DISEASE	2009	Germer Mattias Osterrot Frank Ajgner Zil'Ke Uehrek Kristof Kraus Ehl'Mar Vartenberg-Demand Andrea Vol'F Daniehle Kajzer Zibille Lindner Jurgen Brjukher Kristof Delken Benzhamin	RU2540013C2
DRUGS FOR TREATING DISEASES	2010	Osterrot Frank Uerek Kristof Bryukher Kristof Delken Benzhamin Engling Andre Tsuber Shantal Chelot Niklas Vallmajer Kholger Felp Kirsten Shults Gregor	RU2598719C2
HUMANISED AHTH-CD4 ANTIBODY WITH IMMUNOSUPPRESSIVE PROPERTIES	2004	Vizhden Zhon Jonulajt Khel'Mut	RU2375375C2
COMPOSITION FOR TREATING ARTHRITIS	2009	Fussa Arno Brjun Valeri Asnali Ehlen Bel'Mont Natali Jorgensen Kristian	RU2563360C2
METHOD OF TREATING JOINT INJURIES	2006	Totorajtis Mark Shou Timoti Mark Agarval Sunil Jokum Dehvid Kelman Ehriehlla	RU2457860C2
METHOD AND COMPOSITION FOR REDUCTION OF MICROMOLECULE AGGREGATION UNDER PHYSIOLOGICAL CONDITIONS	2009	Lobo Brajan Lo Sabrina Vang Juchang Dzhon Vong Rita	RU2563823C2
METHODS OF TREATING RHEUMATOID ARTHRITIS USING IL-17 ANTAGONISTS	2011	Mpofu Shefard Richards Khanno Tkhangavelu Kartkhinatkhan Mashasek Mattias	RU2582937C2
METHODS OF TREATING CONDITIONS WITH ANTIBODIES THAT BIND COLONY STIMULATING FACTOR 1 RECEPTOR (CSF1R)	2012	Vong Brajan Masteller Emma Vong Dzhastin Lin Khajshan	RU2670743C9

RU 2 531 548 C2

Authors

Osterrot Frank

Ajgner Zil'Ke

Uehrek Kristof

Vartenberg-Demand Andrea

Rudnev Anatolij

Zol'Dan Mikhaehl'

Brjukher Kristof

Delken Benzhamin

Tsuber Shantal'

Shul'Ts Gregor

Chelot Niklas

Dates

2014-10-20—Published

2009-08-31—Filed