FIELD: medicine.
SUBSTANCE: invention relates to medicine, specifically, oncology, and can be used to treat neoplasia in a subject. To this end, an antibody that binds human colony stimulating factor 1 receptor (CSF1R) is administered to a subject with neoplasia. Antibody blocks binding of colony stimulating factor 1 (CSF1) to CSF1R at such a dose that the amount of CD16+ monocytes decreases by at least 30 %.
EFFECT: invention provides treatment for neoplasia in a subject.
8 cl, 15 dwg, 14 ex, 5 tbl
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