DOSAGE FORMS CONTAINING DOPAMINE AGONISTS FOR PARENTERAL ADMINISTRATION Russian patent published in 2014 - IPC A61K31/48 A61K31/485 A61K47/00 A61K9/00 A61K9/22 A61J3/00 A61P3/10 

FIELD: medicine.

SUBSTANCE: pharmaceutical compositions according to the invention contain at least one dopamine agonist, and a pharmaceutical vehicle comprising a pharmaceutically acceptable permeation enhancer, a pharmaceutically acceptable solubility enhancer, and a pharmaceutically acceptable bioadhesion enhancer. The dosage forms according to the invention have a pharmacological profile, which is described by T_max to approximately 90 minutes after administering the dosage form, and the plasma medicament concentration of at least 50% C_max over the period of time from 90 to 360 minutes after achieving C_max.

EFFECT: improved therapeutic effect as compared to the oral dosage forms of dopamine agonists.

65 cl, 8 dwg, 29 ex