FIELD: medicine.
SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents nanoparticles containing a biodegradable polymer, cyclodextrin or their derivative and a biologically active molecule wherein said biodegradable polymer is a polyvinylmethylether maleic anhydride (PVM/MA) copolymer; and said biologically active molecule is a substance representing a substrate of P-glycoprotein enzyme.
EFFECT: invention provides higher bioavailability of lipophilic oral drugs or those being the substrate of P-glycoprotein enzyme.
9 cl, 7 ex, 9 tbl, 8 dwg
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Authors
Dates
2012-09-10—Published
2008-04-18—Filed