NANOPARTICLES CONTAINING CYCLODEXTRIN AND BIOLOGICALLY ACTIVE MOLECULE, AND USING THEM Russian patent published in 2012 - IPC A61K9/51 A61K31/765 A61K47/40 B82B1/00 

Abstract RU 2460518 C2

FIELD: medicine.

SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents nanoparticles containing a biodegradable polymer, cyclodextrin or their derivative and a biologically active molecule wherein said biodegradable polymer is a polyvinylmethylether maleic anhydride (PVM/MA) copolymer; and said biologically active molecule is a substance representing a substrate of P-glycoprotein enzyme.

EFFECT: invention provides higher bioavailability of lipophilic oral drugs or those being the substrate of P-glycoprotein enzyme.

9 cl, 7 ex, 9 tbl, 8 dwg

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Authors

Aguehros Baso Majte

Sal'Man Khesham Kh.A.

Irache Garreta Khuan Manuehl'

Kampanero Martines Migel' Ankhel'

Dates

2012-09-10Published

2008-04-18Filed